I think asking so plainly is kind of rude. If a girl asked me that and I was a guy I would tell her, "it certainly is not you!" I have this horrible image of a chubby blond asking a boy "so, who do ya like?" and poking him in the stomach as he weakly tries to make her go away.
Who also uses that as a way of making conversation? I would start talking about the weather before using that!