http://www.google.com/search?q=aspartame+kidney

"Sucralose also causes swelling of the liver and kidneys, and CALCIFICATION of the kidney. Note: if you experience kidney pain, cramping, or an irritated bladder after using sucralose in Splenda, stop use immediately. Dr. Janet Starr Hull"
http://www.shirleys-wellness-cafe.com/nutraswt.htm

http://www.google.com/search?q=saccharine+kidney

""Too much saccharine can interfere with liver metabolism and kidney functions. For those who have kidney and liver conditions, the presence of saccharine can pose an immediate threat. Symptoms include feeling nauseous or getting sick," Chiang said."
http://www.taipeitimes.com/News/taiwan/archives/2006/01/17/2003289412