One of may quotes from articles on the ncbi.nlm.nih.gov website:
After a lengthy evaluation process, on
5 May 2006, the EFSA (European Food Safety Authority)
*published a 44-page report (EFSA 2006). *
*A summary comment of the EFSA report on *
ERF study included the following:
The increased incidence of lymphomas/leukaemias
reported in treated rats was unrelated to aspartame,
given the high background incidence of chronic
inflammatory changes in the lungs and the lack of
a positive dose–response relationship. … The
slight increase in incidence of these tumours in rats
fed aspartame is considered to be an incidental
finding of the ERF study and can therefore be dismissed.
(EFSA 2006)
The preneoplastic and neoplastic lesions of the
renal pelvis, ureter and bladder occurring primarily
in female rats along with renal calcification were
most probably treatment-related, at least at the
higher doses. It is widely accepted that the effect is
a high dose effect of irritant chemicals or chemicals
producing renal pelvic calcification as a result of
imbalances in calcium metabolism, specific to the
rat. The Panel considers that these effects are of no
relevance for humans. (EFSA 2006)
And as for
>The feeding of sucralose, a new and high-intensity sweetener
>under regulatory review, resulted in" "an increase in the
>incidences of renal mineralization
What "Diet-Studies" neglects to mention, is that this particular study also notes:
Renal mineralization has been observed in
rats following the feeding of lactose, sodium alginate,
magnesium oxide and in uninephrectomized rats
(rats in which one kidney has been removed) fed
high levels of sodium chloride.
and:
The committee concluded that no
available information on acid-modified starches
would lead one to suspect a hazard to the public when
used at current levels in foods.