I think it's possible that science's assumptions are wrong, and i think it's interesting to think about.
But to me, as far as considering a career in science is concerned, it's completely irrelevant. I'm not studying science for the sake of being right, i'm studying it to:
-get a job, hopefully an interesting one
-have a nice piece of paper or several which will look good on my wall.
-learn interesting things
-use my life to do some good in this world, hopefully.