hmm, I didn't really think I was trying to assume anything about absolute knowledge, only that if all information was known, could an outcome be predicted. Whether there would be some machine or entity capable of calculating it is irrelevant.
I suppose I should have phrased it, does every reaction in the universe follow some natural law (even though we may not understand it yet)? If so, does it then follow that the Human Brain is just another reaction that could itself be predicted?