演出 = direction (of a TV or theatrical performance)
演出家 = a director

演出 also means dramaturgy, stage effect.

I don't know the anime, but I guess its shows the lipstic (or something lipstic-staind) as an important metephor of something and/or the key object which significantly affetcts the storyline.

Perhaps the poster said,
"The director gave the really effective expression/meaning to the lipstick. Excellent!"